Limiting research on molecular targeted therapies in advanced solid cancers: beyond a cost–effectiveness ratio analysis
نویسندگان
چکیده
منابع مشابه
Review: side effects of approved molecular targeted therapies in solid cancers.
Major advances have been achieved in the field of biologically based therapies for cancer in the last few years, and some of the recently approved molecular-targeted therapies are now being used in daily clinical practice. These molecular targets are also expressed in normal cells, which explains the different grades of toxicity, resulting from the disruption of normal cellular function. In gen...
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There is interest in treating cancers by targeting biological “pathways” that are characterized by specific genetic markers. Genetic panel testing offers the potential to evaluate a large number of genetic markers at a single time to identify treatments that target specific pathways. There are some individual markers that have established benefit in certain types of cancers; these situations ar...
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ژورنال
عنوان ژورنال: Biomarkers in Medicine
سال: 2019
ISSN: 1752-0363,1752-0371
DOI: 10.2217/bmm-2019-0216